COUGHLIN tablet

COUGHLIN tablet provides two actions, both mucolytic and cough suppressing.

COMPOSITION

Each tablet contains:

Noscapine (15 mg), Bromhexine HC1(8mg)

PHARMACOLQGY

Noscapine is a centrally acting cough suppressant that has actions and uses similar to Dextromethorphan Hydrobromide. It acts directly on the cough center in the medulla to raise the cough threshold or on the higher centers such as the cerebral cortex (where voluntary coughing is initiated). It differs from some antitussives that it is non-narcotic and therefore the problems associated with narcotic antitussives such as sedation, confusion, bronchospasm should be less frequent.

Bromhexine is a mucolytic expectorant, i.e. it fragments mucus so it is less tenacious and easier to expectorate

INDICATIONS

Relief of symptoms of cough with sputum.

DOSAGE AND ADMINSTRATION

Adults: Take one to two tablets，three times daily or as directed by the physicians.

WARNING AND PRECAUTION

There have been report of hypersensitivity reactions,   anaphylactic reactions, and sever skin such as erythema multiforme, Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and acute generalised exanthematous pustulosis (AGEP) associated with die administration of bromhexine. If symptoms or signs of a progressive skin rash (sometimes associated with blisters or mucosal lesions) are present treatment should be discontinued immediately and medical advice should be sought.

PRECAUTION

COUGHLIN tablet should be contra-indicated in pregnant women and women of child-bearing potential because of potential mutagenic effects. Since mucolytics may disrupt the gastric mucosal barrier, bromhexine should be used with care in patients with a history of peptic ulceration.

It is not recommended to be used in pregnant women.

ADVERSE

Nausea, vomiting, diarrhea,  constipation, headache, dizziness may occur,

Caution is necessary if any of the symptoms occur, continue or bothersome.

STORAGE

Store in dry place. Protect from direct sunlight and keep out of reach of children.

PACKING

20’s in blister pack/box

Reg.No. HK-50595